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วันศุกร์ที่ 28 สิงหาคม พ.ศ. 2552

Function of Pyridoxine

Function of Pyridoxine

In the body, pyridoxine is normally stored as pyridoxal-5-phosphate (PLP), the coenzyme form of the vitamin. It is needed for:
Metabolism of amino acids
Cellular metabolism of carbohydrate, protein and fat.
Formation of neurotransmitters .
Production of nicotinic acid (vitamin B3).

Metabolism of Pyridoxine

PL - pyridoxal PN - pyridoxine PM - pyridoxamine -O feedback inhibition B2 – riboflavin
PMP - pyridoxamine 4-PA - pyridoxic acid PLP - pyridoxal 5-phosphate PNP - pyridoxine 5-phosphate 5-phosphate RBC - red blood cell -

Deficiency and toxicity of Pyridoxine

Factors that may increase vitamin B6 pyridoxine deficiency include alcohol consumption, high protein diets, and antidepressants. Deficiency of vitamin B6 pyridoxine can lead to muscular weakness, anemia, acne, dermatitis and eczema, allergies and asthma, nervousness, irritability and sleep disturbances. Other symptoms can be swollen tongue, ridged nails, arthritis, osteoporosis, and kidney stones.

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